Endocrine Abstracts

Background: Evidence has shown that the use of high doses of statins is associated with lower levels of LDL cholesterol and a decrease in cardiovascular events. Likewise, the use of high doses of statins may increase the risk of myopathy, elevation of liver enzymes, renal failure and cognitive alterations. We conducted a systematic review with a meta-analysis of all RCTs investigating the impact of atorvastatin and ezetimibe therapy on levels of LDL cholesterol vs high doses o...

Background: Despite a high relapse rate, antithyroid drugs (ATDs) remain the first-line therapy of Graves’ disease (GD). Long-term follow-up studies of GD in Spain are scarce. Our aims were to identify clinical differences between patients who relapsed vs those who attained remission and to describe the relapse rate of GD after ATD withdrawal.Methods: We analyzed patients with the first episode of GD who were treated with ATDs during 2010 - 2020, in...

Introduction: The 25hydroxyvitamin(OH)D deficiency has been linked to the risk of postmenopausal fractures and osteoporosis. In Colombia,the prevalence of 25(OH)vitaminD deficiency is high, reaching more than 53% of the total population. It can be stated that hip fracture is one of its most feared complications, with a high risk of mortality and morbidity,which can affect even osteopenic patients. The objective of this study is to assess modifications in hip T-score (using dua...